Magic Mouthwash

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This medication requires a prescription from your doctor.

How to Write a Magic Mouthwash Prescription:

  • 1 Part viscous lidocaine 2%
  • 1 Part Maalox
  • 1 Part diphenhydramine 12.5 mg per 5 ml elixir

Quantity: 120 ml

Sig: Swish, gargle, and spit one to two teaspoonfuls every six hours as needed. Shake well before using.

There are multiple formulations that are called “Magic Mouthwash” used to treat mouth sores and sore throat. Each of these mouthwashes includes different ingredients and strengths although there is a consistency in the types of drugs used. Each mouthwash usually contains an antibiotic, an antihistamine, an antifungal, a corticosteroid, and an antacid. Common ingredients used in magic mouthwash formulations include:

  • Diphenhydramine – an antihistamine that can reduce inflammation and pain. Diphenhydramine is marketed commercially as Benadryl.
  • Nystatin – antifungal for treating candidiasis.
  • Lidocaine – an anesthetic frequently used in topical formulations that can reduce pain by numbing the mouth and throat.
  • Hydrocortisone – steroid that treats inflammation.
  • Tetracycline – antibiotic for treating infection.
  • Maalox/Mylanta – helps the active ingredients stay on the sores and affected areas of the mouth and throat longer.

Magic Mouthwash Directions

The most commonly prescribed directions for magic mouthwash are to swish for two minutes then spit and swallow. This should be done around every four hours. Directions may vary depending on the formulation and what it is being used to treat. After using the mouthwash, drinking and eating should be avoided for about a half an hour so that the medicine will stay on the affected areas.

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