mesalamine suppository

Mesalamine

mesalamine suppository
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This medication requires a prescription from your doctor.

Mesalamine 1000mg suppository
Mesalamine 400mg delayed-release tablet

Mesalamine (also known as 5-aminosalicylic acid) is prescribed to patients to help with ulcerative colitis, a type of bowel disease. It does not cure ulcerative colitis, but it may decrease the number of stools, the amount of blood in the stools, and the rectal bleeding caused by irritation of the colon. Mesalamine is an aminosalicylate anti-inflammatory drug. It is believed to work by blocking the production of certain natural chemicals that may cause pain and swelling.

Mesalamine is available in both a 1000mg suppository and a 400mg delayed-release tablet. The tablets are similar to the discontinued medication Asacol and can help reduce symptoms of ulcerative colitis. Mesalamine can also be combined into a suppository with budesonide — a corticosteroid that reduces inflammation.

It has been shown in studies that a slow-release tablet is more effective as it is better tolerated and less likely to be expelled early. It is most often prescribed to be administered once before bed time but can be prescribed to be used one to three times daily.

Research

  • Efficacy and Safety of Mesalamine Suppositories for Treatment of Ulcerative Proctitis in Children and Adolescents – PubMed
  • Comparative, open, randomized trial of the efficacy and tolerance of slow-release 5-ASA… – PubMed

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