Mesalamine Suppositories


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This medication requires a prescription from your doctor.

Mesalamine 1000mg suppository
Mesalamine 500mg, Budesonide 6mg suppository

Mesalamine (also known as 5-aminosalicylic acid) is prescribed to patients to help with ulcerative colitis, a type of bowel disease. It does not cure ulcerative colitis, but it may decrease the number of stools, the amount of blood in the stools, and the rectal bleeding caused by irritation of the colon. Mesalamine is an aminosalicylate anti-inflammatory drug. It is believed to work by blocking the production of certain natural chemicals that may cause pain and swelling.

Mesalamine is available in both a 1000mg suppository and a 600mg suppository with budesonide. The tablets are similar to the discontinued medication Asacol and can help reduce symptoms of ulcerative colitis. A combination can be made into a suppository with budesonide, which is a corticosteroid that reduces inflammation.

Research has shown that this suppository is safe and effective for the treatment of ulcerative proctitis in pediatric patients. The majority of subjects met both responder and remission criteria of the study after 3 and 6 weeks of treatment.


  • Efficacy and Safety of Mesalamine Suppositories for Treatment of Ulcerative Proctitis in Children and Adolescents – PubMed

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