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Antimalarials for Rheumatic Conditions

The drugs quinacrine, chloroquine, and hydroxychloroquine were all developed as antimalarials but found new applications in treating chronic conditions. The conditions that benefit most from these drugs are those that involve inflammatory processes such as rheumatoid arthritis and lupus. While the exact mechanism of action is not known, many rheumatologists prescribe these medications because of their proven success in relieving symptoms like pain and swelling and preventing the recurrence of…
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Treating Lupus with Antimalarial Drugs

Lupus is a disorder that causes the immune system to target the body’s own tissues and organs leading to inflammation. Several drugs that initially were used to prevent or treat malaria are now also used for treating lupus including quinacrine, chloroquine, and hydroxychlorquine. These drugs treat lupus symptoms by mildly suppressing the immune system, which reduces inflammation throughout the body. What is Lupus? While the exact cause of lupus is…
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What is LDN?

Key Points LDN is a lower dose of the FDA-approved drug naltrexone, which has been used for many years to treat opioid addiction. Evidence continues to grow that LDN can be an effective treatment for a variety of conditions including Crohn’s, lupus, fibromyalgia, and multiple sclerosis. LDN can only be obtained from a compounding pharmacy since the lower dosages of naltrexone are not FDA-approved. LDN Advantages Low cost: LDN is…
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