Mast cell activation syndrome (MCAS) is a rare condition that sometimes is misdiagnosed. There are various resources online that discuss MCAS, its causes, and treatments. However some of these resources have an overly broad scope of what is classified as MCAS. Many patients have some type of mast cell activation issue but do not have MCAS. The diagnosis of MCAS is difficult as it is associated with a variety of…

Mast cell activation syndrome (MCAS) and mastocytosis are two conditions that affect how mast cells function. There is no cure for these conditions and in most cases they are present because of a genetic predisposition. Treatments focus on improving the dermatological, gastrointestinal, respiratory, and other symptoms that result from overproduction of certain chemical mediators. Antihistamines are one of the most frequently used types of medications for managing these symptoms. The…